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Fig. 7 | Cell & Bioscience

Fig. 7

From: miR-26a inhibits atherosclerosis progression by targeting TRPC3

Fig. 7

miR-26a overexpression inhibited activation of the nuclear factor-kappa B (NF-κB) pathway by downregulating TRPC3 in ox-LDL-treated HAECs. a HAECs were transfected with miR-26a, miR-NC, miR-26a + Empty, or miR-26a + TRPC3, followed by treatment with 50 nM ox-LDL for 24 h. Then, the protein levels of p65, p-p65, IκBα and p-IκBα in the treated HAECs were detected by western blot. b HAECs were transfected with anti-miR-26a, anti-miR-NC, anti-miR-26a + si-NC, or anti-miR-26a + si-TRPC3, followed by treatment with 50 nM ox-LDL for 24 h. Then, the protein levels of p65, p-p65, IκBα and p-IκBα in the treated HAECs were detected by western blot

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