Fig. 8

Some miRNAs are selectively enriched in EVs secreted from NSCLC cell lines. a qRT-PCR results showing the expression of miR-20a-5p, miR-20b-5p, miR-30b-5p, miR-451a, miR-665 and miR-122-5p in NSCLC cell lines and the normal control IMR-90 cell line. b qRT-PCR results showing the expression of the above miRNAs in EVs from the conditioned culture medium of NSCLC or IMR-90 cells. c The fold change of expression of the above miRNAs in EVs or cell lysates. d EV vs. cell lysate expression fold changes of miR-451a and miR-122-5p. The qRT-PCR data were normalized to cel-miR-39. Results are presented as mean ± SD