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Table 7 Altered methylation genes mapped to the neuropathic pain signaling pathway by IPA

From: Epigenetic alterations in TRAMP mice: epigenome DNA methylation profiling using MeDIP-seq

Symbol Gene name Log2-fold change Type(s)
GRM3 Glutamate receptor, metabotropic 3 − 3.636 G-protein-coupled receptor
GRIA1 Glutamate receptor, ionotropic, AMPA 1 − 3.167 Ion channel
BDNF Brain-derived neurotrophic factor − 2.373 Growth factor
CREB1 cAMP-responsive element-binding protein 1 − 2.274 Transcription regulator
GRM7 Glutamate receptor, metabotropic 7 − 2.274 G-protein-coupled receptor
GRIN3A Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A − 2.129 Ion channel
MAPK1 Mitogen-activated protein kinase 1 2.048 Kinase
TAC1 Tachykinin, precursor 1 2.408 Other
CAMK1D Calcium/calmodulin-dependent protein kinase ID 2.855 Kinase
TACR1 Tachykinin receptor 1 2.855 G-protein-coupled receptor
KCNN3 Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 3.119 Ion channel
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 3.855 G-protein-coupled receptor