Fig. 2

Aspirin pretreatment decreased the metastasis capacity of colon cancer cells induced by LPS. C26 and HCT116 cells were firstly exposed to aspirin (10 mmol/L) for 24 h and then LPS (10 μg/ml) was used to stimulate colon cancer cells. a Wound healing assay was used to examine the migration of C26 cells. b Transwell assay was employed to detect the metastasis of C26 and HCT116 cells. c Mouse splenic vein metastasis assay was used to observe the metastasis of C26 cells in vivo. d Tumor number was counted. (*P < 0.05; ***P < 0.001)