Fig. 8

Exogenous H₂S restores PC-induced cardioprotection in the aged cardiomyocytes. Exogenous H₂S contributes to recovery of PC-induced cardioprotection by down-regulation of endoplasmic reticulum stress via inhibition of PERK-eIF 2α-ATF 4, IRE 1α-XBP-1 and ATF 6 pathways in the aged cardiomyocytes