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Fig. 5 | Cell & Bioscience

Fig. 5

From: Cloning, expression and identification of KTX-Sp4, a selective Kv1.3 peptidic blocker from Scorpiops pococki

Fig. 5

Affinity of KTX-Sp4 for the turret region mutant of Kv1.1. a Sequence alignments of amino acid residues in the S5-S6 link region between Kv1.1 and Kv1.3. Red letters indicate different amino acid residues in the turret region between Kv1.1 and Kv1.3. b Current traces in the absence (control) or presence of 100 nM KTX-Sp4 on Kv1.1-AEHS/PSGN channels. c Normalized current inhibition by various concentrations of KTX-Sp4 on Kv1.1-AEHS/PSGN channels. Data represent mean ± SE of six experiments

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