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Table 1 Genotype of pups generated by mating heterozygous breeders under different genetic background

From: 14-3-3ζ loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature

Strain\geno

+/+

±

−/−

p value

B6/129P2 F2

22

39

3

0.0052

B6 congenic

58

72

0

< 0.0001

B6-E18.5

16

32

15

0.9879

CD-1

36

73

38

0.9849

FVB/NJ

27

53

25

0.9809

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Cell & Bioscience

ISSN: 2045-3701

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