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Table 1 Genotype of pups generated by mating heterozygous breeders under different genetic background

From: 14-3-3ζ loss leads to neonatal lethality by microRNA-126 downregulation-mediated developmental defects in lung vasculature

Strain\geno +/+ ± −/− p value
B6/129P2 F2 22 39 3 0.0052
B6 congenic 58 72 0 < 0.0001
B6-E18.5 16 32 15 0.9879
CD-1 36 73 38 0.9849
FVB/NJ 27 53 25 0.9809