Fig. 1
From: Combination of EZH2 inhibitor and BET inhibitor for treatment of diffuse intrinsic pontine glioma
H3K27M make the NSCs gain the tumor activity. a Western blot showing the expression level of Flag-tagged-H3K27M or Flag-tagged-H3K27wt, HA-tagged-PDGFB, H3K27me3, H3 and GAPDH. b Soft agar colony assay of PDFGB/H3WT or PDGFB/H3K27M NSCs. Data were represented as mean ± SD, n = 3 independent experiments. ***p < 0.001. c Cck-8 kit was used to evaluate the viability of PDFGB/H3WT or PDGFB/H3K27M NSCs. Data were represented as mean ± SD, n = 3 independent experiments. ***p < 0.001