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Fig. 1 | Cell & Bioscience

Fig. 1

From: Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide to DNA encoding capsid protein L1 of Bovine papillomavirus

Fig. 1

DNA construct of pcDNA3-E7(49-57), pcDNA3-BPVL1, and pcDNA3-BPVL1-E7(49-57). The DNA sequence of HPV16 E7 CTL epitope (aa49-57) and the full-length sequence of BPV1 L1 protein were individually cloned into the pcDNA3 plasmid vector to generate pcDNA3-E7(49-57) and pcDNA3-BPVL1, respectively. The DNA sequence of HPV16-E7aa49-57 epitope was fused to DNA sequence of the full-length BPV1 L1 protein at the C-terminus and cloned into the pcDNA3 plasmid vector to generate the pcDNA3-BPVL1-E7(49-57) fusion construct

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