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Fig. 5 | Cell & Bioscience

Fig. 5

From: Phosphorylation of astrocytic connexin43 by ERK1/2 impairs blood–brain barrier in acute cerebral ischemia

Fig. 5

In vivo administration of ERK inhibitor or siRNA defends ischemia-induced impairment in blood–brain barrier integrity. a SCH772984 treatment protects blood–brain barrier integrity after bilateral common carotid artery occlusion. b siRNA against ERK1/2 treatment protects the blood–brain barrier integrity after ischemia induction. Data is presented as mean ± SEM. *p < 0.05, **p < 0.01 and ***p < 0.001

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