Fig. 6From: Kv1.3 channel blocker (ImKTx88) maintains blood–brain barrier in experimental autoimmune encephalomyelitisEffects of ImKTx88 treatment on the expression of Ang-1 and Tie-2. a Relative expression of Ang-1 and Tie-2 mRNA from the control group, EAE group, ImKTx88 prevention group and ImKTx88 treatment group (n = 6–8) were measured by qRT-PCR. b Western blot showed that levels of Ang-1 and Tie-2 were significantly decreased when EAE was induced, and ImKTx88 could increase their expression (n = 5). GAPDH was used as an internal control. Data are presented as the mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001Back to article page