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Fig. 4 | Cell & Bioscience

Fig. 4

From: Long non-coding RNA MALAT1 contributes to cell apoptosis by sponging miR-124 in Parkinson disease

Fig. 4

Effects of si-MALAT1 and anti-miR-124 on apoptosis of MPP+-intoxicated SH-SY5Y cells. SH-SY5Y cells were transfected with si-MATAL1 or in combination with anti-miR-124, followed by the treatment of 1 mM MPP+ solution for 24 h. a Flow cytometry analysis was performed to examine apoptosis in treated SH-SY5Y cells. b Caspase3 activity was determined by the caspase3 assay kit in treated SH-SY5Y cells. c Western blot was carried out to detect the level of Cleaved Caspase3 in treated SH-SY5Y cells. β-actin was used as the internal control. d Quantification analysis of Cleaved Caspase3. *P < 0.05 vs. control group

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