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Fig. 5 | Cell & Bioscience

Fig. 5

From: Hepatitis B virus promotes cancer cell migration by downregulating miR-340-5p expression to induce STAT3 overexpression

Fig. 5

HBV induces the migration of cancer cells by inducing STAT3 overexpression via downregulation of miR-340-5p expression. a qRT-PCR analysis of the effect of HBV on STAT3 mRNA expression. b Western blot assays show HBV induces high levels of STAT3 expression. d Wound-healing assays show that the forced expression of miR-340-5p mimics rescue HBV-induced wound-healing ability. c, e Representative photographs of Transwell assays: d miR-340-5p mimics rescued HBV-induced cell migration. e Over expression of STAT3 rescued miR-340-5p mimics inhibition and led to a dramatic increase in cell migration. *P < 0.05; **P < 0.01; ***P < 0.001

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