Fig. 4
From: Large is required for normal astrocyte migration and retinal vasculature development
Abnormal astrocyte migration and retinal vasculature in Large PB/PB mutants. a–b GFAP staining showed normal honeycomb pattern of retinal astrocytes in P5 wild-type mice (a), but disorganized astrocyte processes in P5 Large PB/PB mice (b). Dashed lines indicate the border of astrocyte migration. c Retinal astrocytes in P5 Large PB/PB mice migrated more slowly than wild-type mice of the same age. d–f GFAP and GS-isolectin staining of P7 wild-type retinas. g–i GFAP and GS-isolectin staining of P7 Large PB/PB retinas. Scale bars (a, b), 200 μm; scale bar (d–i), 100 μm