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Fig. 7 | Cell & Bioscience

Fig. 7

From: Hsa-let-7c-5p augments enterovirus 71 replication through viral subversion of cell signaling in rhabdomyosarcoma cells

Fig. 7

Modulation of JNK pathway activity by EV71 infection. a The effect of EV71 infection on JNK activity was assessed by Western blotting. RD cells were infected with EV71 (MOI = 5) at the indicated time points, and the data were analyzed by comparison with the mock-infected group. The ratios of the p-JNK1/2 to total JNK1/2 signals are expressed as fold changes compared with the mock-infected group, as quantified using Image J software, as shown in (b). c The effect of UV inactivation of EV71 on JNK activity was assessed by Western blotting. RD cells were infected with UV-inactivated EV71 at the indicated time points, and the data were analyzed by comparison with the mock-infected group. The ratios of the p-JNK1/2 to total JNK1/2 signals are expressed as fold changes compared with the mock-infected group, as quantified using Image J software, as shown in (d). *p < 0.05; **p < 0.01

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