Fig. 2
From: Analysis of Axin2 expression and function in murine models for pancreatic cancer
Characterization of the animal model for acute pancreatitis. a Hyperglycemia was induced in two cohorts (STZ, STZ+Cer) by ip injection of 50 mg/kg streptozotocin on day 1–5 and chronic pancreatitis was then induced in two cohorts (Cer, STZ+Cer) by administration of eight ip injections of cerulein (50 µg/kg) on day 22 and 23; the control groups (Sham, Cer) were treated with the appropriate vehicle solutions. b β-galactosidase staining in tubular complexes of the pancreas in normoglycemic and hyperglycemic Axin2+/lacZ mice was observed after pancreatitis, whereas no β-galactosidase staining was observed in Axin2+/+ mice. Bars 50 μm