Fig. 7From: Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expressionA proposed model illustrating the mechanism by which GCN5 enhances AIB1 expression and promotes proliferation of HCC cells. GCN5 associates with E2F1 and binds to AIB1 promoter to enhance AIB1 transcription by acetylating H3K9 around E2F1 binding site 1 on AIB1 promoterBack to article page