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Fig. 3 | Cell & Bioscience

Fig. 3

From: Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression

Fig. 3

GCN5 knockdown inhibits xenograft tumor formation. a Knockdown of GCN5 inhibited HCC cell tumorigenesis in vivo. 1 × 106 HepG2 control cells, shGCN5-1 and shGCN5-2 cells were subcutaneously injected into dorsal flanks of nude mice, respectively. Five days after cell injection, tumor volume was measured every 2 or 3 days. n = 5, *p < 0.05, **p < 0.01. b GCN5-knockdown tumors showed a significant decrease in tumor volume compared with control tumors. An image of tumors is shown. c Tumor volume was significantly reduced in GCN5-knockdown tumors. d The expression of the PCNA was decreased in GCN5-knockdown tumors

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