Fig. 2

GCN5 knockdown reduces cell proliferation in HCC cell lines. a GCN5 overexpression enhanced cell proliferation in HepG2, Huh-7 and L-O2 cells. Overexpression of GCN5 was confirmed by Western blot analysis. MTT assay was performed to determine cell proliferation rate. *p < 0.05, **p < 0.01. b Proliferation was reduced in stable GCN5-knockdown HepG2 cells, as measured by MTT assay. Down-regulation of GCN5 was confirmed by Western blot analysis. c Knockdown of GCN5 inhibited HCC cell colony formation. *p < 0.05, **p < 0.01