Fig. 4

Effect of E2 in the proliferation and differentiation of hematopoietic progenitors derived from hUCB. a Hematopoietic progenitors (CD34⁺) were harvested from hUCB using MACS and exposed to E2 for 5 and 10 days. Effects of E2 on the proliferation of hUCB-derived hematopoietic progenitors. b Frequencies of ER-α were measured by flow cytometry. c Assessment of the hematopoietic multi-lineage potential of hUCB-derived hematopoietic progenitors treated with E2 for 5 and 10 days. All results are mean ± SD. *p < 0.05, **p < 0.01