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Fig. 3 | Cell & Bioscience

Fig. 3

From: Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway

Fig. 3

Increased number of hemangioblasts and erythroid colony during iPSC hematopoiesis is dependent on ER-α signaling. a Representative image of a hemangioblast derived from hiPSCs (i) Multiple types of hematopoietic CFU (ii) and endothelial cells (iii, stained with CD144) derived from hiPSC-hemangioblasts. b, c Effects of E2, DPN and PPT on the generation of hemangioblasts from hiPSCs and their hematopoietic progenitor capacity. d, e Effects of E2 on the output of CFU-E from hiPSC-derived hemangioblasts were analyzed by flow cytometry. All results are mean ± SD. *p < 0.05, **p < 0.01

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