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Fig. 1 | Cell & Bioscience

Fig. 1

From: Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway

Fig. 1

Temporal expression of ER-α and hematopoietic markers during hiPSC-derived hematopoietic development. a Immunocytochemistry staining for ER-α (green) costained with OCT4 (red) in feeder-free hiPSC cultures. Nuclei were counterstained with DAPI (blue). Scale bar 100 μm. b Frequencies of ER-α and OCT4 in undifferentiated hiPSC cultures by flow cytometry. c Schematic diagram of hematopoietic development from hPSC: hemogenic specification phase (phase I) and hematopoietic commitment phase (phase II). d Temporal expression patterns of ER-α and hematopoietic markers during hiPSC-derived hematopoietic development

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