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Fig. 5 | Cell & Bioscience

Fig. 5

From: Bioinformatic analysis reveals the expression of unique transcriptomic signatures in Zika virus infected human neural stem cells

Fig. 5

Immune specific biological pathways enriched in up-regulated genes. a The biological pathways associated with ZIKV transcript changes were filtered to include top immune specific pathways. b Using a FDR q-value <0.05, several top immune function pathways were enriched for the up-regulated gene set, although none of the pathways were enriched for significant down-regulated transcripts. The q-values for the pathway enrichment are annotated along the left panel as the dot plot. c Using tissue specific expression databases, up- and down-regulated genes were probed for immune related cells and tissues. Innate and adaptive immune system components were represented in both lists. (q < 0.05)

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