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Fig. 5 | Cell & Bioscience

Fig. 5

From: Exogenous H2S modulates mitochondrial fusion–fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state

Fig. 5

NaHS inhibits high glucose (HG)-induced VSMC cell proliferative protein expression. Mitochondrial (a) ROS production were assessed using 5 µM MitoSox. Representative fluorescence images show increased ROS production in the VSMC mitochondria. b Upon stimulation with HG for 24 h, the P27, PCNA and Cyclin D1 protein expression levels were determined using western blot analyses; the results are representative of three independent experiments. *p < 0.05 vs control, **p < 0.01 vs control, # p < 0.05 vs HG and Pal, ## p < 0.01 vs HG and Pal

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