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Fig. 5 | Cell & Bioscience

Fig. 5

From: Baicalein antagonizes acute megakaryoblastic leukemia in vitro and in vivo by inducing cell cycle arrest

Fig. 5

Baicalein possesses anti-AMKL activity in vivo. a 6133 MPL/W515L cells treated with or without baicalein were collected for CD41 staining. The expression of CD41 was analyzed by flow cytometry. b Sublethally irradiated mice were transplanted with 6133 MPL/W515L cells (3 × 105 cells/mouse). Two days after transplantation, the recepient mice were fed with vehicle or baicalein (20 mg/kg body weight) through oral gavage for 10 days and left for survival observation. c The spleen weight from the recipient mice sacrificed on 14 days post transplantation (n = 3, *indicates p < 0.05). d Histological sections of the spleen and lung from recipient mice sacrificed on 14 days post transplantation were stained with Hematoxylin and eosin (H and E). *p < 0.05 as compared to vehicle treatment

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