Low expression of Aldo–keto reductase 1B10 is a novel independent prognostic indicator for nasopharyngeal carcinoma

Table 2 Correlation between AKR1B10 expression levels and the clinicopathologic characteristics of NPC patients

Variables	AKR1B10 expression levels				Sub-total	Fisher’s exact tests		Correlation analysis
Variables	3	2	1	0	Sub-total	Values	p values	r values	p values
Subtotal	15	33	73	79	200
Age (years)
≤45	9	10	31	29	79	4.235	0.239	0.046	0.519
>45	6	23	42	50	121	4.235	0.239	0.046	0.519
Tumor type
Undifferentiation	6	10	16	43	75	18.008	<0.001	0.212	0.003
Differentiation	9	23	57	36	125	18.008	<0.001	0.212	0.003
Neck masses (cm)
0	8	15	26	33	82	2.765	0.848	0.047	0.510
>0, ≤3	4	10	15	13	42
>3	3	8	32	33	76
T-classification
T1/T2	10	21	33	18	82	36.119	<0.001	-0.399	<0.001
T3/T4	5	12	40	61	118	36.119	<0.001	-0.399	<0.001
N classification
N0/N1	12	23	37	26	98	19.746	<0.001	-0.311	<0.001
N2/N3	3	10	36	53	102	19.746	<0.001	-0.311	<0.001
Distant metastasis
Yes	6	6	5	18	35	12.776	0.004	0.011	0.892
No	9	27	68	61	165	12.776	0.004	0.011	0.892
TNM clinical stage
I–II	12	30	67	66	175	3.569	0.302	0.059	0.420
III–IV	3	3	6	13	25	3.569	0.302	0.059	0.420

ISSN: 2045-3701