Fig. 2

Effect of treatment on endothelial expression of ICAM-1. A non-occlusive collar was inserted around the left common carotid artery of normolipidemic NZW rabbits, as described in the legend to Fig. 1. Representative sections of carotid arteries stained for ICAM-1 expression (×40 magnification) are shown in the panels. a a representative section from a control, non-collared artery from a saline-treated animal, b a collared artery section from a saline-treated animal, c a section of a collared artery from an animal treated with indomethacin (IndoH), d a section of a collared artery from a Cu(II)-Indo-treated animal, e a section of a collared artery from an animal treated with Cu(II)-ACM and f a section of a collared artery from an animal treated with Zn(II)-ACM. In g the results are expressed graphically as mean ± SEM (**p < 0.01)