Fig. 1

Effect of treatment on endothelial expression of VCAM-1. Normocholesterolemic NZW rabbits were treated with either saline, IndoH (3 mg/kg), Cu(II)Indo (3 mg/kg), Cu(II)ACM (3 mg/kg) or Zn(II)ACM (3 mg/kg) (n = 4 per group) at the time of peri-arterial collar insertion. The animals were sacrificed 24 h after collar insertion. Representative sections of carotid arteries stained for VCAM-1 expression (×40 magnification) are shown. a a representative control, non-collared artery from a saline-treated animal, b a collared artery section from a saline-treated animal, c a section of a collared artery where the animal is treated with IndoH, d a section of a collared artery from an animal treated with Cu(II)Indo, e a collared artery section from an animal treated with Cu(II)ACM and f a section of a collared artery from an animal is treated with Zn(II)ACM. In g the results are expressed graphically as mean ± SEM (*p < 0.05; **p < 0.01)