Fig. 4

NF-κB signal pathway and anti-apoptotic gene in acute liver injured model. a Western-blot analyzed relevant proteins expression of NF-κB pathway include IκBα, p-IκBα and NF-κB-p65 proteins in CCl₄-treated rats. The more doses of Enbrel were added, the lower expression of p-IκBα and NF-κB-p65 proteins they were, while the expression of IκBα had an opposite effect. b Western-blot and c RT-PCR analyzed anti-apoptosis include Bcl-XL, FHC, XIAP and Bcl-2 in CCl₄-induced rats. As dose of Enbrel were increased, the expression of anti-apoptosis gene declined. We set mRNA expression of these genes as one in each control groups. Data are presented as mean with SD experiments. (*p < 0.05, **p < 0.01)