Fig. 3From: Knockdown of CLIC4 enhances ATP-induced HN4 cell apoptosis through mitochondrial and endoplasmic reticulum pathwaysEffect of CLIC4 on the mitochondrial apoptotic pathway. Representative images (a) and summarized data (b–g) showing the expression levels of CLIC4 (a), Bcl-2 (a, b–c), Bax (a, d–e) and active caspase 3 (a, f–g). HN4 cells were transfected with CLIC4 (+, CLIC4 siRNA) or scrambled (−, Con) siRNA, and treated with (+, +ATP) or without (−, −ATP) 100 μmol/L ATP for 3 h. β-Tubulin was used as a loading control. Values are shown as the mean ± SE. n = 3. *P < 0.05. vs. the control (Con) groupBack to article page