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Fig. 3 | Cell & Bioscience

Fig. 3

From: Knockdown of CLIC4 enhances ATP-induced HN4 cell apoptosis through mitochondrial and endoplasmic reticulum pathways

Fig. 3

Effect of CLIC4 on the mitochondrial apoptotic pathway. Representative images (a) and summarized data (b–g) showing the expression levels of CLIC4 (a), Bcl-2 (a, bc), Bax (a, de) and active caspase 3 (a, fg). HN4 cells were transfected with CLIC4 (+, CLIC4 siRNA) or scrambled (−, Con) siRNA, and treated with (+, +ATP) or without (−, −ATP) 100 μmol/L ATP for 3 h. β-Tubulin was used as a loading control. Values are shown as the mean ± SE. n = 3. *P < 0.05. vs. the control (Con) group

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