Fig. 1
From: Deciphering the role of interleukin-22 in metabolic alterations
IL-22, IL-20, and IL-24 and their receptor complexes. Binding of IL-22, IL-20, and IL-24 to their receptor complexes takes place in two steps: IL-22 initially binds to IL-22R1 while IL-20 and IL-24 primarily interact with IL-20R2 (a). The complete receptor complex for IL-22 consists of IL-22R1 and IL-10R2. IL-20 and IL-24 can use two different receptor complexes: the IL-22R1/IL-20R2 complex and the IL-20R1/IL-20R2 complex (b)