Fig. 1

G-CSF treatment schedule. a Mice were divided into four groups randomly and treated daily with i.p. vehicle or G-CSF (1 µg/time, twice a day) for 7 days after exposure to 4 Gy TBI and then fed sterilely for 1 month after TBI. Sham-irradiated mice were treated in the same way regarded as a control. b The numbers of white blood cells (WBCs), red blood cells (RBCs), Hgb and platelets (PLTs) in peripheral blood were quantified after the mice were killed 1 month later. c Bone marrow nucleated (BMN) cells were quantified 1 month after various treatments. The data are presented as mean ± SEM, six mice/group. **p < 0.005 (vs. control); ^##p < 0.005 (vs. 4 Gy)