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Fig. 4 | Cell & Bioscience

Fig. 4

From: Ouabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase α in mouse

Fig. 4

Effects of ouabain on TAC-induced cardiac hypertrophy in Con and p85-KO mice. Experiments were done as described in “Methods”. Left ventricular wall thickness was monitored by echocardiography before and after 8 weeks of the surgery. Ouabain was infused subcutaneously (50 μg/kg/day) by ALZET osmotic pumps for continuous dosing for the first 4 weeks. a Posterior wall thickness (PWT); b septal wall thickness (SWT) and c relative wall thickness (RWT). n = 6 ~ 7, *P < 0.05 vs. Sham; # P < 0.05 vs. TAC

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