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Fig. 3 | Cell & Bioscience

Fig. 3

From: Ouabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase α in mouse

Fig. 3

Effects of ouabain on hypertrophic growth and hypertrophic marker gene expressions in cultured cardiomyocytes of Con and p85-KO mice. a Comparison of 12 h treatment of ouabain (50 μM) and ET-1 (100 nM) on protein synthesis (3H-leucine incorporation) in Con and p85-KO cardiomyocytes (n = 6); b, c ouabain and ET-1 effects on hypertrophic markers (fetal gene expression) in Con and p85-KO cardiomyocytes (n = 3) and d effects of ouabain, ET-1 and the combination of the two on protein synthesis (3H-phenylalanine incorporation) (n = 9). *P < 0.05 vs. vehi, **P < 0.01 vs. vehi, #P < 0.05 vs. oua

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