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Fig. 1 | Cell & Bioscience

Fig. 1

From: The chemical chaperone sodium 4-phenylbutyrate improves the secretion of the protein CA267T mutant in CHO-K1 cells trough the GRASP55 pathway

Fig. 1

PBA improved the secretion of PCA267T. CHO-K1 cells stably expressing PCA267T were incubated with indicated concentrations of PBA for 48 h. The levels of PC in the cell medium were determined using an ELISA kit. The results are presented as % PC relative to the PC levels in a plasma pool from healthy subjects (set as 100 %) and adjusted to the total protein concentrations in corresponding cell lysates. Results from three independent experiments are presented as mean ± SEM relative to untreated control cells. *p < 0.05, ***p < 0.0005

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