Fig. 1From: Integrated transcriptional profiling and genomic analyses reveal RPN2 and HMGB1 as promising biomarkers in colorectal cancerIdentification of CRC gene signatures using global expression profiles. Microarray analysis was performed using stage II CRC cancer specimens (T1-4), compared to matched mucosal tissue samples (N1-4). a Unsupervised hierarchical clustering of differentially expressed genes was used to identify differentially expressed genes (fold change 1.5, p < 0.05). Over-expressed and under-expressed genes are indicated by red and green colour. The expression level is proportional to colour brightness. Black bars on the left indicate gene clusters A and B, respectively. An expanded view of cluster A (over-expressed genes, b), or cluster B (under-expressed genes, c), with the indicated gene names is shownBack to article page