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Fig. 1 | Cell & Bioscience

Fig. 1

From: Integrated transcriptional profiling and genomic analyses reveal RPN2 and HMGB1 as promising biomarkers in colorectal cancer

Fig. 1

Identification of CRC gene signatures using global expression profiles. Microarray analysis was performed using stage II CRC cancer specimens (T1-4), compared to matched mucosal tissue samples (N1-4). a Unsupervised hierarchical clustering of differentially expressed genes was used to identify differentially expressed genes (fold change 1.5, p < 0.05). Over-expressed and under-expressed genes are indicated by red and green colour. The expression level is proportional to colour brightness. Black bars on the left indicate gene clusters A and B, respectively. An expanded view of cluster A (over-expressed genes, b), or cluster B (under-expressed genes, c), with the indicated gene names is shown

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