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Fig. 5 | Cell & Bioscience

Fig. 5

From: Co-administration with DNA encoding papillomavirus capsid proteins enhances the antitumor effects generated by therapeutic HPV DNA vaccination

Fig. 5

Characterization of BPV1-specific neutralizing antibody responses generated by mice vaccinated with CRT/E7 and/or BPV1 L1 DNA. C57BL/6 mice (three per group) were immunized on days 1, 15, and 30 intradermally using a gene gun with 2 μg of DNA per mouse of CRT/E7 and/or BPV1 L1 DNA. In vitro neutralization assays were performed using BPV1 L1 pseudovirus on twofold dilutions of antisera collected from the mice 2 weeks after the final immunization. Endpoint titers achieving 50 % neutralization are plotted and the means shown as horizontal lines. PI = Pre Immune; L1 = BPV1 L1 DNA vaccine; E7 = CRT/E7 DNA vaccine

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