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Fig. 2 | Cell & Bioscience

Fig. 2

From: Metabolomic profiling of Burkholderia pseudomallei using UHPLC-ESI-Q-TOF-MS reveals specific biomarkers including 4-methyl-5-thiazoleethanol and unique thiamine degradation pathway

Fig. 2

PCA and PLS-DA score plot based on culture supernatant. (a) PCA score plot and (b) PLS-DA score plot generated using MetaboAnalyst based on culture supernatant in positive mode. PLS-DA models were validated using R 2 and Q 2 based on leave one out cross-validation (LOOCV). Five-component model was selected as optimized model with R 2 = 0.99 and Q2 = 0.99. The significance of the model was demonstrated by permutation test with 2000 testing iterations using separation distance and P value <0.001 was obtained. BC, B. cepacia complex; BPS, B. pseudomallei; BT, B. thailandensis; PA, P. aeruginosa; EC, E. coli

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