Fig. 5

MED effectively reduces atherosclerotic lesions in HFD-fed ApoE ^−/− mice. a HFD-fed mice were injected with PBS or 4 mg/kg/day MED every other day for 8 weeks, respectively. At the end points, mice were sacrificed, and atherosclerotic lesions in the descending aorta were detected by Sudan IV staining. b Quantitative analysis of atherosclerotic lesion sizes. Data are presented as the means ± S.D;n = 5 per group. **p < 0.01