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Fig. 1 | Cell & Bioscience

Fig. 1

From: Biologically active, high levels of interleukin-22 inhibit hepatic gluconeogenesis but do not affect obesity and its metabolic consequences

Fig. 1

Endogenous IL-22 does not play a role in the development of obesity and insulin resistance induced by a HFD. a Two-month old IL-22TG6 mice and their littermate controls were fed a HFD or CD for 10 weeks. Serum IL-22 levels were measured. b, c Two-month old IL-22KO mice and their littermate controls were fed a HFD or CD for 10 weeks. Body weight was counted weekly (panel b); GTT and ITT were examined after 10 weeks feeding (panel c). CD; control diet; HFD: high-fat diet. Values represent the mean ± SEM (n = 6-12)

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