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Table 7 Genes with decreased methylation that mapped to the Wnt/β-catenin pathway by IPA

From: Association of aberrant DNA methylation in Apcmin/+ mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

Symbol Gene name log2 Fold Change Location Type(s)
ACVR1C activin A receptor, type IC −3.029 Plasma Membrane kinase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide −2.877 Plasma Membrane enzyme
SOX13 SRY (sex determining region Y)-box 13 −2.877 Nucleus transcription regulator
WIF1 WNT inhibitory factor 1 −2.877 Extracellular Space other
CDH2 cadherin 2, type 1, N-cadherin (neuronal) −2.708 Plasma Membrane other
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha −2.708 Cytoplasm phosphatase
TGFB3 transforming growth factor, beta 3 −2.708 Extracellular Space growth factor
PPP2R1B protein phosphatase 2, regulatory subunit A, beta −2.614 Plasma Membrane phosphatase
CSNK1G3 casein kinase 1, gamma 3 −2.515 Cytoplasm kinase
WNT11 wingless-type MMTV integration site family, member 11 −2.515 Extracellular Space other
MARK2 MAP/microtubule affinity-regulating kinase 2 −2.292 Cytoplasm kinase
WNT7A wingless-type MMTV integration site family, member 7A −2.292 Extracellular Space cytokine
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) −2.167 Nucleus transcription regulator
GJA1 gap junction protein, alpha 1, 43 kDa −2.029 Plasma Membrane transporter
PPP2R2B protein phosphatase 2, regulatory subunit B, beta −2.029 Cytoplasm phosphatase
PPP2R5A protein phosphatase 2, regulatory subunit B’, alpha −2.029 Cytoplasm phosphatase
SFRP2 secreted frizzled-related protein 2 −2.029 Plasma Membrane transmembrane receptor
SOX7 SRY (sex determining region Y)-box 7 −2.029 Nucleus transcription regulator
SOX14 SRY (sex determining region Y)-box 14 −2.029 Nucleus transcription regulator
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) −2.029 Nucleus transcription regulator
TLE3 transducin-like enhancer of split 3 −2.029 Nucleus other
WNT7B wingless-type MMTV integration site family, member 7B −2.029 Extracellular Space other
WNT8B wingless-type MMTV integration site family, member 8B −2.029 Extracellular Space other