Skip to main content

Table 6 Genes with increased methylation that mapped to the Wnt/β-catenin pathway by IPA

From: Association of aberrant DNA methylation in Apcmin/+ mice with the epithelial-mesenchymal transition and Wnt/β-catenin pathways: genome-wide analysis using MeDIP-seq

Symbol Gene name log2 Fold Change Location Type(s)
SOX11 SRY (sex determining region Y)-box 11 3.614 Nucleus transcription regulator
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 3.462 Nucleus transcription regulator
SOX2 SRY (sex determining region Y)-box 2 3.292 Nucleus transcription regulator
WNT5A wingless-type MMTV integration site family, member 5A 3.292 Extracellular Space cytokine
WNT10A wingless-type MMTV integration site family, member 10A 3.100 Extracellular Space other
CDH5 cadherin 5, type 2 (vascular endothelium) 2.877 Plasma Membrane other
DKK3 dickkopf WNT signaling pathway inhibitor 3 2.877 Extracellular Space cytokine
HDAC1 histone deacetylase 1 2.877 Nucleus transcription regulator
PPP2R3A protein phosphatase 2, regulatory subunit B”, alpha 2.877 Nucleus phosphatase
RUVBL2 RuvB-like AAA ATPase 2 2.877 Nucleus transcription regulator
UBD ubiquitin D 2.877 Nucleus other
FZD1 frizzled class receptor 1 2.752 Plasma Membrane G-protein coupled receptor
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.614 Plasma Membrane other
FZD8 frizzled class receptor 8 2.614 Plasma Membrane G-protein coupled receptor
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.614 Nucleus transcription regulator
SOX4 SRY (sex determining region Y)-box 4 2.614 Nucleus transcription regulator
SOX6 SRY (sex determining region Y)-box 6 2.614 Nucleus transcription regulator
APC2 adenomatosis polyposis coli 2 2.292 Cytoplasm enzyme
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.292 Cytoplasm other
CSNK2A1 casein kinase 2, alpha 1 polypeptide 2.292 Cytoplasm kinase
MMP7 matrix metallopeptidase 7 (matrilysin, uterine) 2.292 Extracellular Space peptidase
NR5A2 nuclear receptor subfamily 5, group A, member 2 2.292 Nucleus ligand-dependent nuclear receptor
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 2.292 Nucleus enzyme
TGFB2 transforming growth factor, beta 2 2.292 Extracellular Space growth factor
WNT2 wingless-type MMTV integration site family member 2 2.292 Extracellular Space cytokine
AKT3 v-akt murine thymoma viral oncogene homolog 3 2.100 Cytoplasm kinase
FRAT1 frequently rearranged in advanced T-cell lymphomas 2.100 Cytoplasm other
WNT2B wingless-type MMTV integration site family, member 2B 2.100 Extracellular Space other
WNT16 wingless-type MMTV integration site family, member 16 2.029 Extracellular Space other