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Table 1 Flow cytometry employing propidium iodide and ethanol fixation demonstrating cell cycle progression

From: A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell lines

  Sub G 1 G 1 S G 2 M
MCF-7 cells
Vehicle-treated cells 1.16% 73.53% 11.43% 13.86%
EMBS-treated cells 36%* 3.14% 10.92% 50%*
Actinomycin D-treated cells 62.7%* 4.46% 8.72% 24.13%
MDA-MB-231
Vehicle-treated cells 0.64% 68.95% 15.16% 15.23%
EMBS-treated cells 27.9%* 2.66% 6.45% 63%*
Actinomycin D-treated cells 71%* 4.97% 5.38% 18.69%
MCF-12A cells
Vehicle-treated cells 0.78% 68.33% 12.42% 18.45%
EMBS-treated cells 32.5%* 4.14% 11.69% 51.7%*
Actinomycin D-treated cells 45.4%* 4.06% 9.85% 40.7%*
  1. A * demonstrates a statistically significant P value of <0.05 when compared to vehicle-treated cells.