Figure 7
From: A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell lines
Caspase 7 activation by EMBS. Caspase 7 activity of vehicle-treated MCF-7 (A), MDA-MB-231 (B) MCF-12A cells (C), EMBS-treated MCF-7 (D), MDA-MB-231 (E), MCF-12 A cells (F) and actinomycin D-treated MCF-7 (G), MDA-MB-231 (H) and MCF-12A (I). Data showed an increase in the number of cells with increased caspase 7 activity after exposure to EMBS when compared to cells vehicle-treated cells. Actinomycin D-treated cells were used as a positive control for apoptosis and caspase activation and displayed significant elevated caspase 7 activity when compared to vehicle-treated cells.