Alteration of miRNAs after dengue virus infection in Ae. albopictus mosquitoes. (A) Down-regulated miRNAs. The horizontal axis indicates the fold change, and the vertical axis indicates normalized miRNAs expression. Blue indicates the greatly regulated miRNAs. (B) Up-regulated miRNAs. (C) miRNAs that were down-regulated and up-regulated more than 50-fold. (D) The 14 most highly expressed miRNAs in control and infected mosquitoes. T-tests were used for the comparison of miRNAs expression. The P values were performed on the data with the significance threshold selected as 0.05.