Upregulation of Nrf2-regulated genes HMOX-1 ( HO-1) and SLC7A11 by SWT or z-LIG in MCF-10A cells. MCF-10A cells were seeded at a density of 2 × 105 cells per well in a 6-well tissue culture plate and treated with SWT or z-LIG for 6 hours. RNA was extracted and quantitative RT-PCR was performed. Data shown are means from three replicates; bars, S.E. *: p <0.05; ***: p < 0.0001 compared to control.