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Table 3 Association of GRIK1 genetic polymorphisms with CAA complications in Taiwanese KD children by multivariate regression analysis

From: Genetic variants of glutamate receptor gene family in Taiwanese Kawasaki disease children with coronary artery aneurysms

GRIK1 genetic polymorphisms

Odds ratio

95% CI

p value

Full model (adjusted by fever duration and first IVIG used time)

  rs466013

2.12

1.22-3.65

0.011

  rs425507

2.16

1.26-3.76

0.009

  rs388700

2.16

1.26-3.76

0.009

  rs402280

1.89

1.09-3.21

0.028

  1. GRIK1, glutamate receptor, ionotropic, kainate 1; IVIG, Intravenous immunoglobulin; CAA, Coronary artery aneurysm; CI, confidence interval.
  2. Full model shows results from a logistic regression model including the indicated predictors, fever duration (days) and first IVIG used time (number of days after the first day of fever).
  3. Bold italic are significant at p value <0.05.