Integrin αvβ6 and transcriptional factor Ets-1 act as prognostic indicators in colorectal cancer

Cell & Bioscience

Table 1 Patients characteristic and the expression of intgerin αvβ6 and transcriptional factor Ets-1

Factor	N	αvβ6			P	Ets-1			P
		Negative	Low	High		Negative	Low	High
Age
<60 Y	62	34	16	12		27	23	12
>60 Y	96	67	14	15	0.127	40	36	20	0.964
Gender
Male	115	75	20	20		49	43	23
Female	43	26	10	7	0.705	18	16	9	0.991
Location
Colon	127	83	24	20		55	48	24
Rectum	31	18	6	7	0.641	12	11	8	0.688
Tumor size
<2 cm	15	9	4	2		6	6	3
2 ~ 5 cm	109	70	22	17		47	40	22
>5 cm	34	22	4	8	0.624	14	13	7	0.999
Differentiation
Well	28	22	4	2		15	9	4
Moderate	93	67	16	10		41	37	15
Poor	27	11	8	8		10	10	7
Unknown	10	1	2	7	0.000	1	3	6	0.035
Duke’s phase
A + B	92	59	20	13		40	34	18
C + D	66	42	10	14	0.366	27	25	14	0.942
T stage
T1	48	31	8	9		19	18	11
T2	70	42	16	12		28	30	12
T3	33	24	4	5		18	9	6
T4	7	4	2	1	0.851	2	2	3	0.470
N stage
N0	68	56	6	6		39	21	8
N1	67	33	18	16		22	28	17
N2	23	12	6	5	0.001	6	10	7	0.015
M stage
M0	130	93	24	13		60	52	18
M1	28	8	6	14	0.000	7	7	14	0.000
TNM stage
I&II	66	56	5	5		32	23	11
III	64	37	19	8		28	29	7
IV	28	8	6	14	0.000	7	7	14	0.000
Histopathological type
Tubular adenocarcinoma	134	85	26	23		58	52	24
Mucinous adenocarcinoma	15	10	2	3		6	4	5
Other type	9	6	2	1	0.955	3	3	3	0.826

ISSN: 2045-3701