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Figure 3 | Cell & Bioscience

Figure 3

From: Peptidylarginine deiminase IV promotes the development of chemoresistance through inducing autophagy in hepatocellular carcinoma

Figure 3

PADI4 enhanced chemoresistance of hepatocellular carcinoma cells in vivo. (A) PADI4 was overexpressed in SMMC-7721 cells and then the cells (5 × 106) to perform subcutaneous administration in the nude mice armpit area. After implantation, recipients were injected in tumor in situ with 5-Fu (30 mg/kg) every 3 days. After 27 days of implantation, the animals were sacrificed and tumors were dissected. (B) The tumor weight and volume of each groups were measured after been removed from the mice. (*P < 0.05)

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