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Table 3 Univariate and multivariate analyses of prognostic variables

From: SIRT1 expression is associated with lymphangiogenesis, lymphovascular invasion and prognosis in pN0 esophageal squamous cell carcinoma

Variables Univariate analysis Multivariate analysis
P a P b HR (95.0% CI)a P a HR (95.0% CI)b P b
Age 0.928 0.832     
Gender 0.192 0.243     
Weight loss 0.573 0.578     
Length of tumor 0.685 0.623     
Tumor location 0.358 0.292     
Differentiation 0.017 0.023 1.302 (0.861-1.971) 0.211 1.271 (0.835-1.934) 0.262
T status <0.001 <0.001 1.828 (1.176-2.842) 0.007 1.742 (1.116-2.720) 0.015
Stage <0.001 <0.001 1.567 (1.032-2.381) 0.035 1.538 (1.010-2.342) 0.045
VEGF-C 0.172 0.258     
LVI <0.001 <0.001 1.782 (1.106-2.872) 0.018 1.702 (1.050-2.757) 0.031
LVD 0.030 0.017 1.146 (0.720-1.823) 0.565 1.244 (0.777-1.991) 0.364
SIRT1 <0.001 <0.001 1.784 (1.061-3.001) 0.029 1.711 (1.013-2.890) 0.045
  1. aDisease free survival;
  2. bOverall survival;
  3. CI confidence interval.